Ritazole-D
Pantoprazole acts by selectively inhibiting the H+/K+-ATPase enzyme in the secretory canaliculus of the stimulated parietal cell. Domperidone stimulates GI activity by acting as a competitive antagonist at dopamine D2-receptors.
Each enteric coated tablet contains
Domperidone - 10 mg
Pantoprazole - 40 mg
As directed by the physician.
Lactation. Pantoprazole: Not recommended in child <12 years. Long-term therapy may lead to bacterial overgrowth in the GIT. Domperidone: Increases serum prolactin levels resulting to galactorrhoea in females and gynaecomastia in males. Hypertensive crisis in patients with phaeochromocytoma.
Other Drug Interactions
Care should be exercised when domperidone is administered in combination with MAO inhibitors
Side effects : Diarrhea, constipation, indigestion, skin rash
Ritazole-D is available as a strip of 10 capsules
